Over-the-counter allergy relief options include oral antihistamines, nasal sprays, and other products designed for different allergy symptoms. Common antihistamine active ingredients include cetirizine, fexofenadine, levocetirizine, loratadine, and diphenhydramine. Compare the Drug Facts label for the exact product you are considering.

Cetirizine, fexofenadine, and levocetirizine are different antihistamine active ingredients used in OTC allergy medicines. They can differ in labeled directions, strengths, precautions, and drowsiness considerations, so compare each product's Drug Facts label rather than comparing milligram amounts alone.

Yes. Some antihistamines are commonly marketed as non-drowsy options, while others may cause drowsiness in some people. Review the warnings on the specific product and understand how it affects you before driving or performing activities that require alertness.

Many over-the-counter antihistamines are labeled for common allergy symptoms such as sneezing, runny nose, and itchy or watery eyes. Compare active ingredients and labeled uses to find an option that matches the symptoms you want to relieve.

Start with the active ingredient and strength on the Drug Facts label. Fexofenadine is associated with Allegra®, cetirizine with Zyrtec®, levocetirizine with Xyzal®, and loratadine with Claritin®. Products containing the same active ingredient and strength may still differ in inactive ingredients, dosage format, package size, manufacturer, and labeling.