Money-Back Guarantee | Free US Shipping – No Minimum!

Diarrhea Relief

24/7 Friendly Support

Available 7 Days a Week

Big-grin Guarantee

Big-grin Guarantee

Free Shipping & Returns

Free Shipping & Returns

Diarrhea Relief

Diarrhea Relief

Shop over-the-counter products that help control diarrhea symptoms, including loperamide HCl, multi-symptom diarrhea and gas relief, softgels, and value-size caplets. Compare active ingredients, formats, symptom coverage, and package sizes.
Pharmacist Owned
Free U.S. Shipping on all U.S. orders
Money-Back Guarantee
Secure Checkout
18 products
DBS LABS Diarrhea Relief - 200 Caplets
DBS LABS Diarrhea Relief - 200 Caplets
$20.85
Subscribe & Save
$21.95
One-time Purchase
DBS LABS Diarrhea Relief - 96 Caplets
DBS LABS Diarrhea Relief - 96 Caplets
$13.25
Subscribe & Save
$13.95
One-time Purchase
Loperamax Diarrhea Relief, Loperamide 2mg - 250 Caplets
Loperamax Diarrhea Relief, Loperamide 2mg - 250 Caplets
$26.96
Subscribe & Save
$29.95
One-time Purchase
WELMATE Diarrhea Relief - Loperamide 2mg, 24 Softgels (Generic Imodium)
WELMATE Diarrhea Relief - Loperamide 2mg, 24 Softgels (Generic Imodium)
$7.16
Subscribe & Save
$7.95
One-time Purchase
WELMATE Diarrhea Relief - Loperamide 2mg, 24 Caplets (Generic Imodium)
WELMATE Diarrhea Relief - Loperamide 2mg, 24 Caplets (Generic Imodium)
$4.28
Subscribe & Save
$4.75
One-time Purchase
WELMATE Extra Strength Gas Relief - Simethicone 125mg, 365 Softgels (Generic Gas-X)
WELMATE Extra Strength Gas Relief - Simethicone 125mg, 365 Softgels (Generic Gas-X)
$12.56
Subscribe & Save
$13.95
One-time Purchase
GAS X Extra Strength Gas Relief - Simethicone 125mg, 120 Softgels
GAS X Extra Strength Gas Relief - Simethicone 125mg, 120 Softgels
Sold out
IBS Labs Anti-Diarrheal & Anti-Gas - Loperamide 2mg & Simethicone 125mg, 100 Caplets (Generic Immodium Multi Symptom Relief)
IBS Labs Anti-Diarrheal & Anti-Gas - Loperamide 2mg & Simethicone 125mg, 100 Caplets (Generic Immodium Multi Symptom Relief)
$23.70
Subscribe & Save
$24.95
One-time Purchase
WELMATE Anti-Diarrheal & Anti-Gas - Loperamide 2mg & Simethicone 125mg, 24 Caplets (Generic Immodium Multi Symptom Relief).
WELMATE Anti-Diarrheal & Anti-Gas - Loperamide 2mg & Simethicone 125mg, 24 Caplets (Generic Immodium Multi Symptom Relief).
$6.95
Subscribe & Save
$6.95
One-time Purchase
RUGBY Extra Strength Gas Relief - Simethicone 125mg, 60 Chewable Tablets (Generic Gas-X)
RUGBY Extra Strength Gas Relief - Simethicone 125mg, 60 Chewable Tablets (Generic Gas-X)
$8.55
Subscribe & Save
$9.50
One-time Purchase
MAJOR Extra Strength Gas Relief - Simethicone 125mg, 30 Softgels (Generic Gas-X)
MAJOR Extra Strength Gas Relief - Simethicone 125mg, 30 Softgels (Generic Gas-X)
$6.75
Subscribe & Save
$7.50
One-time Purchase
PEPTO BISMOL Upset Stomach Relief & Antidiarrheal - Bismuth Subsalicylate, 12 fl oz (3 pack)
PEPTO BISMOL Upset Stomach Relief & Antidiarrheal - Bismuth Subsalicylate, 12 fl oz (3 pack)
$34.95
Subscribe & Save
$34.95
One-time Purchase
LACTAID Fast Act Lactase Enzyme Supplement - 120 Caplets
LACTAID Fast Act Lactase Enzyme Supplement - 120 Caplets
$33.95
Subscribe & Save
$33.95
One-time Purchase
RUGBY Ultra Strength Gas Relief - Simethicone 180mg, 60 Softgels (Generic Phazyme)
RUGBY Ultra Strength Gas Relief - Simethicone 180mg, 60 Softgels (Generic Phazyme)
$7.43
Subscribe & Save
$8.25
One-time Purchase
MAJOR Gas Relief - Simethicone 80mg, 100 Chewable Tablets
MAJOR Gas Relief - Simethicone 80mg, 100 Chewable Tablets
$7.16
Subscribe & Save
$7.95
One-time Purchase
GERI-CARE Gas Relief - Simethicone 80mg, 100 Chewable Tablets (Generic Gas-X)
GERI-CARE Gas Relief - Simethicone 80mg, 100 Chewable Tablets (Generic Gas-X)
$7.43
Subscribe & Save
$8.25
One-time Purchase
MAJOR Anti Diarrheal - Loperamide 1mg, 4 oz (Generic Immodium)
MAJOR Anti Diarrheal - Loperamide 1mg, 4 oz (Generic Immodium)
$8.06
Subscribe & Save
$8.95
One-time Purchase
BEANO Gas Relief - Ultra 800, 180 Tablets
BEANO Gas Relief - Ultra 800, 180 Tablets
Sold out

Product Selection Guide

How to Choose the Right Diarrhea Relief Product

Compare diarrhea relief products by active ingredient, symptoms, dosage form, and package size. Many OTC products use loperamide HCl, the same active ingredient found in Imodium A-D®. Single-ingredient loperamide products help control diarrhea symptoms, while formulas combining loperamide with simethicone also address bloating, pressure, and gas-related cramps.

Choose single-ingredient loperamide for diarrhea symptoms

Loperamide HCl is an over-the-counter anti-diarrheal ingredient used to control diarrhea symptoms, including traveler’s diarrhea. Products with loperamide HCl 2 mg may be compared to Imodium A-D® by reviewing the active ingredient and strength.

Choose a multi-symptom formula when diarrhea occurs with gas

Some products combine loperamide HCl with simethicone, similar to multi-symptom Imodium® products. Loperamide controls diarrhea symptoms, while simethicone helps relieve bloating, pressure, and cramps commonly associated with gas.

Compare formats and package sizes

Caplets and softgels offer different dosage formats. Smaller packages may be convenient for travel, while value-size bottles provide a larger supply for the medicine cabinet.

Helpful Answers

Diarrhea Relief Frequently Asked Questions

What is loperamide HCl?

Loperamide HCl is an over-the-counter anti-diarrheal active ingredient used to control symptoms of diarrhea, including traveler’s diarrhea. Loperamide HCl 2 mg is also the active ingredient found in Imodium A-D®.

What is the difference between loperamide and simethicone?

Loperamide helps control diarrhea symptoms. Simethicone is an anti-gas ingredient that helps relieve bloating, pressure, and cramps associated with gas. Some multi-symptom products combine both ingredients.

Are generic loperamide products the same as Imodium A-D®?

Products containing loperamide HCl 2 mg use the same active ingredient and strength as Imodium A-D®. Products may still differ in inactive ingredients, dosage format, package size, manufacturer, and labeling.

Which medicines stop diarrhea?

OTC medicines that may help control diarrhea include loperamide HCl and bismuth subsalicylate.

Loperamide HCl, the active ingredient in Imodium A-D®, slows intestinal movement and helps reduce frequent, loose stools.

Bismuth subsalicylate, found in products such as Pepto-Bismol®, may help relieve mild diarrhea along with nausea, indigestion, or upset stomach.

Which over-the-counter medications work best for diarrhea?

The best OTC option depends on the symptoms.

Loperamide HCl is commonly used to control frequent, loose stools.

Loperamide combined with simethicone may be useful when diarrhea occurs with gas, bloating, pressure, or cramps.

Bismuth subsalicylate may be appropriate when diarrhea occurs with nausea, indigestion, or upset stomach.

Always compare the active ingredients and follow the Drug Facts label.

Which medicines stop diarrhea?

The over-the-counter medications Loperamide HCL and Simethicone are effective at treating the symptoms of diarrhea. Loperamide reduces the frequency of bowel movements. Simethicone treats symptoms of pain that are associated with gas buildup.

How many anti-diarrheal pills are safe to take?

Anti-diarrheal medications are sold in different formulations, with differing levels of potency. You should always consult the instructions on the package to determine how many anti-diarrheal pills you should take.

Which over-the-counter (OTC) medications work best for diarrhea?

The OTC medication that works best for you will depend on your medical history. Loperamide HCL and Simethicone are both effective. However, you should avoid Loperamide if you have ulcerative colitis or other conditions that cause bloody stool. You should not take Simethicone if you take medications for thyroid conditions.

How do anti-diarrhea medications work?

The anti-diarrhea medication Loperamide HCL works by slowing down the movements of the gut. This allows the body to absorb more water before the stool passes through the body. This results in firmer, less-frequent bowel movements.

}