Loperamide HCl is an over-the-counter anti-diarrheal active ingredient used to control symptoms of diarrhea, including traveler’s diarrhea. Loperamide HCl 2 mg is also the active ingredient found in Imodium A-D®.

Loperamide helps control diarrhea symptoms. Simethicone is an anti-gas ingredient that helps relieve bloating, pressure, and cramps associated with gas. Some multi-symptom products combine both ingredients.

Products containing loperamide HCl 2 mg use the same active ingredient and strength as Imodium A-D®. Products may still differ in inactive ingredients, dosage format, package size, manufacturer, and labeling.

OTC medicines that may help control diarrhea include loperamide HCl and bismuth subsalicylate.

Loperamide HCl, the active ingredient in Imodium A-D®, slows intestinal movement and helps reduce frequent, loose stools.

Bismuth subsalicylate, found in products such as Pepto-Bismol®, may help relieve mild diarrhea along with nausea, indigestion, or upset stomach.

The best OTC option depends on the symptoms.

Loperamide HCl is commonly used to control frequent, loose stools.

Loperamide combined with simethicone may be useful when diarrhea occurs with gas, bloating, pressure, or cramps.

Bismuth subsalicylate may be appropriate when diarrhea occurs with nausea, indigestion, or upset stomach.

Always compare the active ingredients and follow the Drug Facts label.